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  • D

    ATATÜRK ÜNİVERSİTESİ

    2009 - 2015
    Doktora

    FEN BİLİMLERİ ENSTİTÜSÜ/BİYOKİMYA (DR)/

    Tez Adı: Karayemiş meyvesinden (Prunus laurocerasus L.) glutatyon s-transferaz enziminin saflaştırılması, karakterizasyonu ve kinetik özelliklerinin incelenmesi
  • Y

    YÜZÜNCÜ YIL ÜNİVERSİTESİ

    2007 - 2009
    Yüksek Lisans

    FEN BİLİMLERİ ENSTİTÜSÜ/KİMYA (YL) (TEZLİ)/

    Tez Adı: Iğdır elmasından polifenol oksidaz enziminin saflaştırılması ve bazı özelliklerinin incelenmesi
  • L

    YÜZÜNCÜ YIL ÜNİVERSİTESİ

    1999 - 2004
    Lisans

    EĞİTİM FAKÜLTESİ/MATEMATİK VE FEN BİLİMLERİ EĞİTİMİ BÖLÜMÜ/KİMYA ÖĞRETMENLİĞİ PR./

    Tez Adı:
Yıl: Makale Başlığı Kapsam Yazar(lar): Dergi Adı: Cilt: Sayı: Link:
2021 2-methylindole analogs as cholinesterases and glutathione S-transferase inhibitors: Synthesis, biological evaluation, molecular docking, and pharmacokinetic studies Uluslararası ÇETİN ADNAN, BURSAL ERCAN, TÜRKAN FİKRET Arabian Journal of Chemistry 14 12 http://dx.doi.org/10.1016/j.arabjc.2021.103449
2021 Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including docking study Uluslararası BOY SONGÜL, TÜRKAN FİKRET, BEYTUR MURAT, ARAS ABDÜLMELİK, AKYILDIRIM ONUR, KARAMAN HALİDE SEDEF, YÜKSEK HAYDAR BIOORGANIC CHEMISTRY 107 https://www.sciencedirect.com/science/article/abs/pii/S0045206820318228
2021 Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on glutathione S-transferase, cholinesterases enzymes and molecular docking studies Uluslararası TÜRKAN FİKRET, ÇALIMLI MEHMET HARBİ, SAYDAN KANBEROĞLU GÜLŞAH, KARAMAN MUHAMMET Journal of Biomolecular Structure and Dynamics 39 9 http://dx.doi.org/10.1080/07391102.2020.1763200
2021 Synthesis of novel 1,2,3 triazole derivatives and assessment of their potential cholinesterases, glutathione S-transferase enzymes inhibitory properties: An in vitro and in silico study Uluslararası ÇELİK FATİH, TÜRKAN FİKRET, ARAS ABDÜLMELİK, ATALAR MEHMET NURİ, SEDEF KARAMAN HALİDE, ÜNVER YASEMİN, KAHRİMAN NURAN BIOORGANIC CHEMISTRY 107 https://www.sciencedirect.com/science/article/abs/pii/S0045206820319040
2021 Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies Uluslararası BURSAL ERCAN, TÜRKAN FİKRET, BULDURUN KENAN, TURAN ÖZEK NEVİN, ARAS ABDÜLMELİK, ÇOLAK NAKİ, MURAHARI MANIKANTA, C. YERGERI MAYUR BIOMETALS 34 https://link.springer.com/article/10.1007/s10534-021-00287-z#citeas
2021 The effects of\n Daucus carota\n extract against PC3, PNT1a prostate cells, acetylcholinesterase, glutathione S\u2010transferase, and α\u2010glycosidase; an in vitro\u2013in silico study Uluslararası ATALAR MEHMET NURİ, ARAS ABDÜLMELİK, TÜRKAN FİKRET, Barlak Neslisah, YILDIKO ÜMİT, KARATAS OMER FARUK, ALMA MEHMET HAKKI Journal of Food Biochemistry 45 http://dx.doi.org/10.1111/jfbc.13975
2018 Identification of chemical components from the Rhizomes of Acorus calamus L. with gas chromatography-tandem mass spectrometry (GC-MS\\MS) Uluslararası ATALAR MEHMET NURİ, TÜRKAN FİKRET Journal of the Institute of Science and Technology 8 4
2019 Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives Uluslararası TÜRKAN FİKRET,ÇETİN ADNAN,TASLİMİ PARHAM,Karaman Halide Sedef,GÜLÇİN İLHAMİ ARCHIV DER PHARMAZIE 352 6 http://dx.doi.org/10.1002/ardp.201800359
2018 The behavior of some chalcones on acetylcholinesterase and carbonic anhydrase activity Uluslararası ASLAN HATİCE ESRA, DEMİR YELİZ, ÖZASLAN MUHAMMET SERHAT, TÜRKAN FİKRET, BEYDEMİR ŞÜKRÜ, KÜFREVİOĞLU ÖMER İRFAN DRUG AND CHEMICAL TOXICOLOGY 42 6 http://dx.doi.org/10.1080/01480545.2018.1463242
2018 Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes Uluslararası GÜLÇİN İLHAMİ,TASLİMİ PARHAM,Aygün Aynur,Sadeghian Nastaran,Bastem Enes,KÜFREVİOĞLU ÖMER İRFAN,TÜRKAN FİKRET,ŞEN FATİH INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 119 http://dx.doi.org/10.1016/j.ijbiomac.2018.08.001
2016 The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII Uluslararası GÜLÇİN İLHAMİ,Scozzafava Andrea,Supuran Claudiu T,AKINCIOĞLU HÜLYA,KÖKSAL ZEYNEP,TÜRKAN FİKRET,Alwase Saleh JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 31 6 http://dx.doi.org/10.3109/14756366.2015.1094470
2021 Synthesis, Spectroscopic Analysis, and\n in Vitro/in Silico\n Biological Studies of Novel Piperidine Derivatives Heterocyclic Schiff\u2010Mannich Base Compounds Uluslararası BOY SONGÜL, ARAS ABDÜLMELİK, TÜRKAN FİKRET, AKYILDIRIM ONUR, BEYTUR MURAT, SEDEF KARAMAN HALİDE, MANAP SEVDA, YÜKSEK HAYDAR Chemistry & Biodiversity 18 http://dx.doi.org/10.1002/cbdv.202100433
2014 Purification and Characterization of Glutathione S Transferase from Laurel Fruit Laurucerasus Officinalis Roem and Inhibition the Effects of Some Pesticides on Enzyme Activity Ulusal TÜRKAN FİKRET,BALCI Neslihan,ŞAKİROĞLU HALİS Muş Alparslan Üniversitesi Fen Bilimleri Dergisi 2 2 https://dergipark.org.tr/tr/pub/msufbd
2018 The toxicological impact of some avermectins on human erythrocytes glutathione S-transferase enzyme Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,ATALAR MEHMET NURİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 10 http://dx.doi.org/10.1002/jbt.22205
2018 Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α‐glycosidase enzymes inhibitors: The novel N,N′‐bis‐cyanomethylamine and alkoxymethylamine derivatives Uluslararası TASLİMİ PARHAM,ÇAĞLAYAN CÜNEYT,Farzaliev Vagif,Nabiyev Oruj,SUJAYEV EFSUN,TÜRKAN FİKRET,KAYA RÜYA,GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 4 http://doi.wiley.com/10.1002/jbt.22042
2018 Some pyrazoles derivatives: Potent carbonic anhydrase, α-glycosidase, and cholinesterase enzymes inhibitors Uluslararası TÜRKAN FİKRET,ÇETİN ADNAN,TASLİMİ PARHAM,GÜLÇİN İLHAMİ ARCHIV DER PHARMAZIE 351 10 http://doi.wiley.com/10.1002/ardp.201800200
2018 Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects Uluslararası ÇETİN ADNAN,TÜRKAN FİKRET,Taslimi Parham,GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 33 3 http://dx.doi.org/10.1002/jbt.22261
2018 The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,TASLİMİ PARHAM,GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 3 http://doi.wiley.com/10.1002/jbt.22041
2019 Phytochemical Content, Antidiabetic, Anticholinergic, and Antioxidant Activities of Endemic\n Lecokia cretica\n Extracts Uluslararası ARAS ABDÜLMELİK,BURSAL ERCAN,TÜRKAN FİKRET,TOHMA HATİCE,KILIÇ ÖMER,GÜLÇİN İLHAMİ,KÖKSAL EKREM CHEMISTRY & BIODIVERSITY 16 10 https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.201900341
2019 Spectroscopic and Structural Characterization, Enzyme Inhibitions, and Antioxidant Effects of New Ru(II) and Ni(II) Complexes of Schiff Base Uluslararası BULDURUN KENAN,TURAN ÖZEK NEVİN,ARAS ABDÜLMELİK,MANTARCI ASİM,TÜRKAN FİKRET,BURSAL ERCAN CHEMISTRY & BIODIVERSITY 16 8 http://dx.doi.org/10.1002/cbdv.201900243
2019 The effects of some cephalosporins on acetylcholinesterase and glutathione S-transferase: an in vivo and in vitro study Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,DEMİR YELİZ,ERTAŞ FATMA,BEYDEMİR ŞÜKRÜ ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY 125 3 https://www.tandfonline.com/doi/full/10.1080/13813455.2018.1452037
2019 Investigation of Inhibition Effects of Some Natural Phenolic Compounds on Glutathione S-transferase (GST), Acetylcholinesterase (AChE), Butyrylcholinesterase (BChE), alpha-Amylase, and alpha-Glycosidase: Antidiabetic, Anticholinergics, Antiparasitic study Uluslararası TÜRKAN FİKRET JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN 41 4 https://inis.iaea.org/search/searchsinglerecord.aspx?recordsFor=SingleRecord&RN=50070995
2019 Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials Uluslararası Taslimi Parham,TÜRKAN FİKRET,ÇETİN ADNAN,BURHAN HAKAN,KARAMAN MUHAMMET,BİLDİRİCİ İSHAK,GÜLÇİN İLHAMİ,ŞEN FATİH BIOORGANIC CHEMISTRY 92 http://dx.doi.org/10.1016/j.bioorg.2019.103213
2019 The effects of some antibiotics from cephalosporin groups on the acetylcholinesterase and butyrylcholinesterase enzymes activities in different tissues of rats Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,Taslimi Parham,GÜLÇİN İLHAMİ ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY 125 1 https://www.tandfonline.com/doi/full/10.1080/13813455.2018.1427766
2019 Purification and characterization of glutathione S-transferase from blueberry fruits (Vaccinium arctostaphylos L.) and investigated of some pesticide inhibition effects on enzyme activity Uluslararası BALCI NESLİHAN,TÜRKAN FİKRET,ŞAKİROĞLU HALİS,AYŞENUR AYGÜN,ŞEN FATİH Heliyon 5 4 https://www.sciencedirect.com/science/article/pii/S2405844018353957
2016 Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes Uluslararası GÜLÇİN İLHAMİ,Andrea Scozzafava,Supuran Claudiu,KÖKSAL ZEYNEP,TÜRKAN FİKRET,çetinkaya songül,Bingöl Zeynep,HUYUT ZÜBEYİR,Saleh Alwasel JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 31 6 https://www.tandfonline.com/doi/full/10.3109/14756366.2015.1135914
2020 Investigation of the effects of cephalosporin antibiotics on glutathione S-transferase activity in different tissues of rats in vivo conditions in order to drug development research Uluslararası TÜRKAN FİKRET, HUYUT ZÜBEYİR, TASLIMI PARHAM, HUYUT MEHMET TAHİR, GÜLÇİN İLHAMİ DRUG AND CHEMICAL TOXICOLOGY 43 4 http://dx.doi.org/10.1080/01480545.2018.1497644
2018 Polyphenolic Content, Antioxidant Potential and Antimicrobial Activity of Satureja boissieri Uluslararası ARAS ABDÜLMELİK, BURSAL ERCAN, ALAN YUSUF, TÜRKAN FİKRET, ALKAN MEHMET HÜSEYİN, KILIÇ ÖMER IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION 37 6 http://www.ijcce.ac.ir/mobile/article_32113.html
2020 Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes Uluslararası BULDURUN KENAN, TURAN ÖZEK NEVİN, BURSAL ERCAN, ARAS ABDÜLMELİK, MANTARCI ASİM, ÇOLAK NAKİ, TÜRKAN FİKRET, GÜLÇİN İLHAMİ Journal of Biomolecular Structure and Dynamics http://dx.doi.org/10.1080/07391102.2020.1802340
2020 Biochemical constituent, enzyme inhibitory activity, and molecular docking analysis of an endemic plant species, Thymus migricus Uluslararası ARAS ABDÜLMELİK, TÜRKAN FİKRET, YILDIKO ÜMİT, ATALAR MEHMET NURİ, KILIÇ ÖMER, ALMA MEHMET HAKKI, BURSAL ERCAN CHEMICAL PAPERS 75 3 https://link.springer.com/article/10.1007/s11696-020-01375-z
2019 Investigation of the toxicological and inhibitory effects of some benzimidazole agents on acetylcholinesterase and butyrylcholinesterase enzymes Uluslararası TÜRKAN FİKRET ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY 127 2 http://dx.doi.org/10.1080/13813455.2019.1618341
2020 Determination of anticancer properties and inhibitory effects of some metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, alpha-glycosidase of some compounds with molecular docking study Uluslararası TÜRKAN FİKRET, TASLIMI PARHAM, SAKAR MUBARAK ABDALREAQ, ARAS ABDÜLMELİK, ERDEN YAVUZ, ÇELEBİOĞLU HASAN UFUK, TÜZÜN BURAK, AĞIRTAŞ MEHMET SALİH, GÜLÇİN İLHAMİ Journal of Biomolecular Structure and Dynamics https://www.tandfonline.com/doi/abs/10.1080/07391102.2020.1768901
2020 Cholinesterases, α-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus Uluslararası Taslimi Parham,TURHAN KADİR,TÜRKAN FİKRET,SEDEF KARAMAN HALİDE,TURGUT ZUHAL,GÜLÇİN İLHAMİ BIOORGANIC CHEMISTRY 97 http://dx.doi.org/10.1016/j.bioorg.2020.103647
2020 2H‐Indazolo[2,1‐b]phthalazine‐trione derivatives: Inhibition on some metabolic enzymes and molecular docking studies Uluslararası TASLIMI PARHAM, TÜRKAN FİKRET, TURHAN KADİR, SEDEF KARAMAN HALİDE, TURGUT ZUHAL, GÜLÇİN İLHAMİ JOURNAL OF HETEROCYCLIC CHEMISTRY 57 8 http://dx.doi.org/10.1002/jhet.4019
2019 Synthesis, spectroscopic properties, crystal structures, antioxidant activities and enzyme inhibition determination of Co(II) and Fe(II) complexes of Schiff base Uluslararası BULDURUN KENAN,TURAN ÖZEK NEVİN,BURSAL ERCAN,MANTARCI ASİM,TÜRKAN FİKRET,Taslimi Parham,GÜLÇİN İLHAMİ RESEARCH ON CHEMICAL INTERMEDIATES 46 1 http://dx.doi.org/10.1007/s11164-019-03949-3
2020 Novel benzo[b]xanthene derivatives: Bismuth(III) triflate‐catalyzed one‐pot synthesis, characterization, and acetylcholinesterase, glutathione S‐transferase, and butyrylcholinesterase inhibitory properties Uluslararası TURHAN KADİR, PEKTAS BEGÜM, TÜRKAN FİKRET, Tuğcu Fatma, TURGUT ZÜHAL, TASLIMI PARHAM, SEDEF KARAMAN HALİDE, GÜLÇİN İLHAMİ ARCHIV DER PHARMAZIE 353 http://dx.doi.org/10.1002/ardp.202000030
2018 Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties Uluslararası TASLİMİ PARHAM,Osmanova Sabiya,ÇAĞLAYAN CÜNEYT,TÜRKAN FİKRET,Serdarova Sabira,Farzaliev Vagif,SUJAYEV EFSUN,Sadeghian Nastaran,GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 9 http://doi.wiley.com/10.1002/jbt.22191
2018 Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with iN/i -salicyloil- iN/i ′-maleoil-hydrazine as anticholinergic and antidiabetic agents Uluslararası Gondolova Gulnar, TASLİMİ PARHAM, Majidov Ajdar, Farzaliev Vagif, SUJAYEV AFSUN, Huseynova Mansura, ŞAHİN ONUR, YALÇIN BAHATTİN, TÜRKAN FİKRET, GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 9 http://doi.wiley.com/10.1002/jbt.22197
2020 Metal contained Phthalocyanines with 3,4-Dimethoxyphenethoxy substituents: their anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies Uluslararası TASLIMI PARHAM, TÜRKAN FİKRET, ARAS ABDÜLMELİK, ERDEN YAVUZ, ÇELEBİOĞLU HASAN UFUK, TÜZÜN BURAK, AĞIRTAŞ MEHMET SALİH, GÜLÇİN İLHAMİ Journal of Biomolecular Structure and Dynamics 40 http://dx.doi.org/10.1080/07391102.2020.1844051
2018 Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities Uluslararası TASLİMİ PARHAM, SUJAYEV AFSUN, TÜRKAN FİKRET, Garibov Emin, HUYUT ZÜBEYİR, Farzaliev Vagif, MAMEDOVA SEVGİ, GÜLÇİN İLHAMİ JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 32 2 http://doi.wiley.com/10.1002/jbt.22019
2020 Comparison of the protective effects of curcumin and caffeic acid phenethyl ester against doxorubicin\u2010induced testicular toxicity Uluslararası HUYUT ZÜBEYİR, ALP HAMİT HAKAN, YAMAN TURAN, KELEŞ ÖMER FARUK, YENER ZABİT, TÜRKAN FİKRET, AYENGİN KEMAL ANDROLOGIA 53 2 https://onlinelibrary.wiley.com/doi/abs/10.1111/and.13919
2019 Glutathione S-Transferase: Purification and Characterization of from Cherry Laurel (Prunus laurocerasus L.) and the Investigation In Vitro Effects of Some Metal Ions and Organic Compounds on Enzyme Activity Uluslararası TÜRKAN FİKRET,AYŞENUR AYGÜN,ŞAKİROĞLU HALİS,ŞEN FATİH BioNanoScience 9 3 https://link.springer.com/article/10.1007/s12668-019-00636-w
2019 Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors Uluslararası TÜRKAN FİKRET, ÇETİN ADNAN, TASLIMI PARHAM, KARAMAN MUHAMMET, GÜLÇİN İLHAMİ BIOORGANIC CHEMISTRY 86 https://www.sciencedirect.com/science/article/pii/S0045206818314202?casa_token=uIfudj0SG7UAAAAA:E5NWTq_L-fxZQ_SxZAHd3RHbuR3VHvmQAqWduQ2RXppuZz3eEy_tmuyDbBUToDETIZi1atE7afl_
2020 Toxicological effects of some antiparasitic drugs on equine liver glutathione S-Transferase enzyme activity Uluslararası TÜRKAN FİKRET, ÇALIMLI MEHMET HARBİ, AKGÜN AYHAN, Gulbagca Fulya, ŞEN FATİH JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 180 https://www.sciencedirect.com/science/article/abs/pii/S073170851932432X
2020 Benzenesulfonamide derivatives as potent acetylcholinesterase, α-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies Uluslararası TASLIMI PARHAM, IŞIK MESUT, TÜRKAN FİKRET, DURGUN MUSTAFA, TÜRKEŞ CÜNEYT, GÜLÇİN İLHAMİ, BEYDEMİR ŞÜKRÜ Journal of Biomolecular Structure and Dynamics https://www.tandfonline.com/doi/abs/10.1080/07391102.2020.1790422
2020 ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn Uluslararası TÜRKAN FİKRET, ATALAR MEHMET NURİ, ARAS ABDÜLMELİK, GÜLÇİN İLHAMİ, BURSAL ERCAN BIOORGANIC CHEMISTRY 94 https://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=3&SID=D2VF9pf21l8fpTpPnMT&page=2&doc=14&cacheurlFromRightClick=no
2020 Influence of some β-lactam drugs on selected antioxidant enzyme and lipid peroxidation levels in different rat tissues Uluslararası TÜRKAN FİKRET, HUYUT ZÜBEYİR, BAŞBUĞAN YILDIRAY, GÜLÇİN İLHAMİ DRUG AND CHEMICAL TOXICOLOGY 43 1 http://dx.doi.org/10.1080/01480545.2019.1608230
2021 Synthesis and in silico studies of Novel Ru(II) complexes of Schiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl)methyl]-2(3H)-benzoxazolone compounds as potent Glutathione S-transferase and Cholinesterases Inhibitor Uluslararası ADIGÜZEL RAGIP, TÜRKAN FİKRET, YILDIKO ÜMİT, ARAS ABDÜLMELİK, EVREN ENES, ÖNKOL TİJEN JOURNAL OF MOLECULAR STRUCTURE 1231 http://dx.doi.org/10.1016/j.molstruc.2021.129943
2018 Glutatyon S-Transferaz Enzim Aktivitesi Üzerine Amoksilin ve Vankomisin Hidroklorid Hidratın Etkisi: Bir in vitro çalışma Ulusal TÜRKAN FİKRET, ATALAR MEHMET NURİ Journal of the Institute of Science and Technology 8 2
2019 In vivo biochemical evaluations of some β-lactam group antibiotics on glutathione reductase and glutathione S- transferase enzyme activities Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,HUYUT MEHMET TAHİR,ÇALIMLI MEHMET HARBİ LIFE SCIENCES 231 231 https://www.sciencedirect.com/science/article/abs/pii/S0024320519304989
2021 Synthesis, Characterization, Enzyme Inhibitory Activity, and Molecular Docking Analysis of a New Series of Thiophene-Based Heterocyclic Compounds Uluslararası ÇETİN ADNAN, TÜRKAN FİKRET, BURSAL ERCAN, MURAHARI MANIKANTA RUSSIAN JOURNAL OF ORGANIC CHEMISTRY 57 4 https://link.springer.com/content/pdf/10.1134/S107042802104014X.pdf
2019 Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer's disease Uluslararası TÜRKAN FİKRET,Taslimi Parham,SALTAN FATMA ZERRİN JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 33 8 https://onlinelibrary.wiley.com/doi/abs/10.1002/jbt.22340
2021 Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods Uluslararası BURSAL ERCAN, YILMAZ MUSTAFA ABDULLAH, IZOL EBUBEKIR, TÜRKAN FİKRET, ATALAR MEHMET NURİ, Murahari Manikanta, ARAS ABDÜLMELİK Biophysical Chemistry 277 http://dx.doi.org/10.1016/j.bpc.2021.106629
2022 Co and Zn Metal Phthalocyanines with Bulky Substituents: Anticancer, Antibacterial Activities and Their Inhibitory Effects on Some Metabolic Enzymes with Molecular Docking Studies Uluslararası TÜRKAN FİKRET, TASLIMI PARHAM, CABİR BEYZA, AĞIRTAŞ MEHMET SALİH, ERDEN YAVUZ, ÇELEBİOĞLU HASAN UFUK, TÜZÜN BURAK, BURSAL ERCAN, GÜLÇİN İLHAMİ POLYCYCLIC AROMATIC COMPOUNDS https://www.tandfonline.com/doi/abs/10.1080/10406638.2021.1893194
2021 Synthesis, enzymes inhibitory properties and characterization of 2- (bis (4-aminophenyl) methyl) butan-1-ol compound: Quantum simulations, and in-silico molecular docking studies Uluslararası YILDIKO ÜMİT, TÜRKAN FİKRET, Tanriverdi Aslihan Aycan, Ata Ahmet Cagri, ATALAR MEHMET NURİ, ÇAKMAK İSMAİL Journal of the Indian Chemical Society 98 http://dx.doi.org/10.1016/j.jics.2021.100206
2021 Investigation of spectroscopic, thermal, and biological properties of FeII, CoII, ZnII, and RuII complexes derived from azo dye ligand Uluslararası TURAN ÖZEK NEVİN, BULDURUN KENAN, ADIGÜZEL RAGIP, ARAS ABDÜLMELİK, TÜRKAN FİKRET, BURSAL ERCAN Journal of Molecular Structure 1244 http://dx.doi.org/10.1016/j.molstruc.2021.130989
Yıl: Bildiri Başlığı Kapsam: Yazar(lar): Etkinlik Adı: Link:
2020 Synthesis of Novel Ru(II) Complexes of Shiff Base Derivatives of 3-[(4-Amino- 5-thioxo-1,2,4-triazole-3-yl)methyl]-2(3h)-Benzoxazolone and Investigation of their Inhibition Effects Comparatively by the Docking Program Uluslararası ADIGÜZEL RAGIP, TÜRKAN FİKRET, ARAS ABDÜLMELİK, YILDIKO ÜMİT, EVREN ENES, ÖNKOL TİJEN 3RD INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY & FUNCTIONAL MATERIALS PCFM-2020 https://ozal.edu.tr/etkin/the-3rd-international-conference-on-physical-chemistry-and-functional-materials-pcfm-2020/
2020 Comparison of Inhibition Effects of Shiff Base Derivatives of 3-[(4-Amino-5- thioxo-1,2,4-triazole-3-yl)methyl]-2(3h)-Benzoxazolone and their Novel Ru(II) Complexes Uluslararası ADIGÜZEL RAGIP, TÜRKAN FİKRET, ARAS ABDÜLMELİK, YILDIKO ÜMİT, EVREN ENES, ÖNKOL TİJEN 3RD INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY & FUNCTIONAL MATERIALS PCFM-2020 https://ozal.edu.tr/etkin/the-3rd-international-conference-on-physical-chemistry-and-functional-materials-pcfm-2020/
2019 BAZI İLAÇLARIN ASETİLKOLİNESTERAZ ENZİMİ ÜZERİNE İNHİBİSYON ETKİLERİNİN ARAŞTIRILMASI Uluslararası TÜRKAN FİKRET,TİMUR SELMA 6. Uluslararası Mesleki ve Teknik Bilimler Kongresi
2019 ESSİTALOPRAM VE MİRTAZAPİN İLAÇLARININ GLUTATYON STRANSFERAZ VE ASETİLKOLİNESTERAZ ENZİMLERİ ÜZERİNE İNHİBİSYON ETKİLERİNİN İNCELENMESİ Uluslararası TÜRKAN FİKRET 3. Uluslararası Avrupa Fen- Matematik- Mühendislik ve Sağlık Bilimleri Kongresi
2018 Investigation of the inhibition effects of some avamectin varieties on glutathione S-transferase enzyme Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,ATALAR MEHMET NURİ 1st INTERNATIONAL BALKAN CHEMISTRY CONGRESS
2018 IN VİVO EFFECTS OF CEFAZOLİN, CEFUROXİME, AND CEFAPERAZON ON THE CARBONİC ANHYDRASE ACTİVİTY İN DİFFERENT RAT TİSSUES TİME DEPENDENTLY Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR 1st INTERNATIONAL HEALTH SCIENCE AND LIFE CONGRESS
2018 Inhibition behaviour of some antibiotics of glutathione S-transferase and acetyl cholinesterase activities: in vitro and in vivo Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR 7th World congress oxidative stress, calcium signaling and TRP channels
2018 Inhibitory Effect of Tannic Acid on Acetylcholinesterase, Butyrylcholinesterase, α‐Glycosidase and α‐Amylase Enzymes Uluslararası TÜRKAN FİKRET,Taslimi Parham,SALTAN FATMA ZERRİN 3rd International PSE Symposium on Natural Products in Cancer Prevention and Therapy Trends in Methods and Modelling
2018 Yeni GST İnhibitörleri Olarak Bazı Benzimidazoller Uluslararası TÜRKAN FİKRET,ÇALIMLI MEHMET HARBİ,AKGÜN AYHAN 1. ınternational Iğdır Congress on Multidisciplinary Studies
2018 ACTIONS OF SELECTED ANTIBIOTICS FROM CEPHALOSPORIN GROUPS ON THE ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE ENZYME ACTIVITIES IN DIFFERENT TISSUES OF RATS TIME DEPENDENTLY: IN VIVO STUDY Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,Taslimi Parham 1st INTERNATIONAL VETERINARY BIOCHEMISTRY AND CLINICAL BIOCHEMISTRY CONGRESS
2017 Effect of some antibiotics on Glutathione-S-transferase activity in kidney, heart and liver tissues Uluslararası TÜRKAN FİKRET,HUYUT ZÜBEYİR,Taslimi Parham,HUYUT Mehmet Tahir,GÜLÇİN İLHAMİ International Biochemistry Congress-2017 / 28. Ulusal Biyokimya Kongresi
2016 The effects of amoxicillin and vancomycin hydrochloride hydrate on glutathione S transferase enzyme activity GST E C 2 5 1 18 Uluslararası TÜRKAN FİKRET 2nd International Turkic World Conference on Chemical Sciences and Technologies ITWCCST
2016 RESEARCHİNG OF THE INHIBITION OF SOME METAL IONS GLUTATHIONE S TRANSFERASE GST ENZYME ACTIVITY TO THE ISOLATED FROM BLUEBERRY Vaccinium Arctostaphylos L Uluslararası Balcı Neslihan,TÜRKAN FİKRET,ŞAKİROĞLU HALİS 2nd International Turkic World Conference on Chemical Sciences and Technologies
2015 Purification and Characterization of Glutathione S transferase From Laurel Fruit Prunus Laurucerasus L Research The Effects of Some Metal Ions on Enzyme Activity Uluslararası TÜRKAN FİKRET,ŞAKİROĞLU HALİS,Balcı Neslihan International Turkish World Conference on Chemical Sciences and Technologies (ITWCCST) ITWCCST
2015 Yaban mersini meyvesinden Vaccinium myrtillus saflaştırılan Glutatyon S transferaz enzim aktivitesi üzerine bazı kimyasalların inhibisyon etkilerinin incelenmesi Ulusal Balcı Neslihan,TÜRKAN FİKRET,ŞAKİROĞLU HALİS 27. Ulısal Kimya Kongresi, www.kimya2015.org
2015 Glutatyon S-Tansferaz Enziminin (GST, E.C. 2.5.1.18) Karayemiş Meyvesinden (Prunus Laurocerasus) Saflaştırılması ve Bazı Organik Bileşiklerin İnhibisyon Etkilerinin Araştırılması Ulusal TÜRKAN FİKRET,ŞAKİROĞLU HALİS,Balcı Neslihan 15th Chromatography Congress http://www.bingol.edu.tr/documents/KROMATOGRAFI%202015%20Kongre%20Kitap%C3%A7----U-AK%20%C3%9CN-VERS-TES-.pdf
2014 Purification and Characterization of Glutathione S transferase From Laurel Fruit Prunus Laurucerasus L Research The Effects of Some Pesticides on Enzyme Activity Uluslararası TÜRKAN FİKRET,ŞAKİROĞLU HALİS,Balcı Neslihan International Congress of the Molecular Biology Association
2010 Iğdır Elmasından Polifenol Oksidaz Enziminin saflaştırılması ve Bazı Özelliklerinin İncelenmesi Ulusal TÜRKAN FİKRET,DEMİR HALİT Kromatografi Kongresi
Yıl Kitap Adı Bölüm: Katkı Düzeyi:
Yıl Tez Adı Yazar: Tür: Durum:
2020 4-aminotetrahidrokinolin türevlerinin sentezi ve asetilkolinesteraz enzimi üzerine inhibisyon etkilerinin incelenmesi ERCAN OĞUZ Yüksek Lisans Tamamlandı
2021 Piperazin grubu içeren sülfonamid türevlerinin sentezi ve glutatyon S- transferaz enzimi üzerine inhibisyon etkilerinin incelenmesi TUBA ÇELİK Yüksek Lisans Tamamlandı
2022 1,4- DİAZOSİKLOHEKZAN ANA İSKELETİ İÇEREN BAZI SÜLFANOMİD TÜREVLERİNİN ANTİOKSİDAN ÖZELLİKLERİ İLE α-GLİKOSİDAZ VE α- AMİLAZ ENZİMLERİ ÜZERİNE İNHİBİSYON ETKİLERİNİN İNCELENMESİ BETÜL GÜVEN Yüksek Lisans Tamamlandı
Akademik Yıl Ders Adı Eğitim Düzeyi:
2020-2021 Genel Kimya Önlisans
2020-2021 Hormon Biyokimyası Önlisans
2020-2021 Klinik Biyokimya Önlisans
2020-2021 Biyokimya Önlisans
2019-2020 Biyokimya Önlisans
2019-2020 Laboratuvar Kimyası Önlisans
2019-2020 Klinik Biyokimya Önlisans
2019-2020 Genel Kimya Önlisans
2020-2021 Antioksidan Maddeler ve Serbest Radikaller Yüksek Lisans
2020-2021 Enzimatik Analiz Yöntemleri Yüksek Lisans
2019-2020 Antioksidan Maddeler ve Serbest Radikaller Yüksek Lisans
2019-2020 Enzimatik Analiz Yöntemleri Yüksek Lisans
2019-2020 Biyomakromoleküllerin İzolasyon,Saflaştırma ve Karekterizasyon Teknikleri Yüksek Lisans
2020-2021 Biyokimya LaboratuvarTeknikleri Yüksek Lisans
2020-2021 İleri Biyokimya Yüksek Lisans
2019-2020 Biyokimya LaboratuvarTeknikleri Yüksek Lisans
2019-2020 İleri Biyokimya Yüksek Lisans
2011-2012 Genel Kimya II Lisans
2011-2012 Genel Kimya I Lisans
2010-2011 Genel Kimya II Lisans
2010-2011 Genel Kimya I Lisans
2014-2015 Biyokimya Lisans
2013-2014 Bitki Biyokimyası Lisans
2013-2014 Biyokimya Lisans
2013-2014 Kimya Lisans
2012-2013 Bitki Biyokimyası Lisans
2012-2013 Biyokimya Lisans
2012-2013 Kimya Lisans
2011-2012 Kimya Lisans
2010-2011 Kimya Lisans
Ders Adı 1. Hafta: 2. Hafta: 3. Hafta: 4. Hafta: 5. Hafta: 6. Hafta: 7. Hafta: 8. Hafta: 9. Hafta: 10. Hafta: 11. Hafta: 12. Hafta: 13. Hafta: 14. Hafta:
Proje Adı Görev: Tür:
Yeni Sentezlenen 1H-Pirazol-4- (5H) -il Diazen Türevlerinin Glutatyon S-transferaz, Asetilkolin esteraz, Bütirilkolin esteraz ve α- Glukozidaz Enzimleri Üzerine İnhibisyon Etkilerinin İncelenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Doksorubisin Uygulamasının Sıçanların Akciğer Dokusunda Karbonik Anhidraz, Glutatyon S- transferaz ve Glutatyon Redüktaz Enzim Aktiviteleri ile ilişkisi: Kurkumin'in Etkisi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
4-Aminotetrahidrokinolin Türevlerinin Sentezi ve Asetilkolinesteraz Enzimi Üzerine İnhibisyon Etkilerinin İncelenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Streptozotosin İle İndüklenen Diyabetli Sıçanlarda Astragalus Brachycalyx Fischer Bitkisinin Kök Ekstraktının İyileştirici Etkilerinin Araştırılması Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Bazı Antibiyotiklerin Glutatyon S-Transferaz ve Asetilkolin Esteraz Enzim Aktiviteleri Üzerine İn vitro ve İn vivo İnhibisyon Etkilerinin Belirlenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Diyabetik nefropatisi olan hastalarda metil arjinin düzeylerinin değerlendirilmesi Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Doksorubisin ile indüklenen testis yaralanmasında Kaffeik Asit Fenetil Ester ve Kurkuminin koruyucu etkilerinin Karştırılması Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Sefazolin, Sefuroksim ve Sefaperazon ilaçlarının karaciğer, böbrek ve beyin dokularında lipid peroksidasyonu ve bazı antioksidan enzim aktivitelerine etkilerinin incelenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Piperazin Grubu İçeren Sülfonamid Türevlerinin Sentezi ve Glutatyon S- transferaz Enzimi Üzerine İnhibisyon Etkilerinin İncelenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Bazı Antidepresan İlaçların Glutatyon S-transferaz ve Kolinesteraz Enzimleri Üzerine inhibisyon Etkilerinin İncelenmesi Yürütücü Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
Patent Adı Buluş Sahipleri: Kategori: Kapsam:
Yıl Ödül Adı Kurum: Tür: Açıklama:
Kurum Durum
Tarih Görev Birim: Bitiş Tarihi:
2021 MYO/Yüksekokul Müdürü IĞDIR ÜNİVERSİTESİ
2021 Dekan Yardımcısı IĞDIR ÜNİVERSİTESİ
2013 MYO/Yüksekokul Müdürü IĞDIR ÜNİVERSİTESİ 2017